Publications

2016
Stein DJ, Karam EG, Shahly V, Hill ED, King A, Petukhova M, Atwoli L, Bromet EJ, Florescu S, Haro JM. {Post-traumatic stress disorder associated with life-threatening motor vehicle collisions in the WHO World Mental Health Surveys}. BMC Psychiatry. 2016;16.Abstract
© 2016 The Author(s).Background: Motor vehicle collisions (MVCs) are a substantial contributor to the global burden of disease and lead to subsequent post-traumatic stress disorder (PTSD). However, the relevant literature originates in only a few countries, and much remains unknown about MVC-related PTSD prevalence and predictors. Methods: Data come from the World Mental Health Survey Initiative, a coordinated series of community epidemiological surveys of mental disorders throughout the world. The subset of 13 surveys (5 in high income countries, 8 in middle or low income countries) with respondents reporting PTSD after life-threatening MVCs are considered here. Six classes of predictors were assessed: socio-demographics, characteristics of the MVC, childhood family adversities, MVCs, other traumatic experiences, and respondent history of prior mental disorders. Logistic regression was used to examine predictors of PTSD. Mental disorders were assessed with the fully-structured Composite International Diagnostic Interview using DSM-IV criteria. Results: Prevalence of PTSD associated with MVCs perceived to be life-threatening was 2.5 {%} overall and did not vary significantly across countries. PTSD was significantly associated with low respondent education, someone dying in the MVC, the respondent or someone else being seriously injured, childhood family adversities, prior MVCs (but not other traumatic experiences), and number of prior anxiety disorders. The final model was significantly predictive of PTSD, with 32 {%} of all PTSD occurring among the 5 {%} of respondents classified by the model as having highest PTSD risk. Conclusion: Although PTSD is a relatively rare outcome of life-threatening MVCs, a substantial minority of PTSD cases occur among the relatively small proportion of people with highest predicted risk. This raises the question whether MVC-related PTSD could be reduced with preventive interventions targeted to high-risk survivors using models based on predictors assessed in the immediate aftermath of the MVCs.
Bromet EJ, Atwoli L, Kawakami N, Navarro-Mateu F, Piotrowski P, King AJ, Aguilar-Gaxiola S, Alonso J, Bunting B, Demyttenaere K. {Post-traumatic stress disorder associated with natural and human-made disasters in the World Mental Health Surveys}. Psychological Medicine. 2016.Abstract
Copyright © Cambridge University Press 2016Background: Research on post-traumatic stress disorder (PTSD) following natural and human-made disasters has been undertaken for more than three decades. Although PTSD prevalence estimates vary widely, most are in the 20–40{%} range in disaster-focused studies but considerably lower (3–5{%}) in the few general population epidemiological surveys that evaluated disaster-related PTSD as part of a broader clinical assessment. The World Mental Health (WMH) Surveys provide an opportunity to examine disaster-related PTSD in representative general population surveys across a much wider range of sites than in previous studies. Method: Although disaster-related PTSD was evaluated in 18 WMH surveys, only six in high-income countries had enough respondents for a risk factor analysis. Predictors considered were socio-demographics, disaster characteristics, and pre-disaster vulnerability factors (childhood family adversities, prior traumatic experiences, and prior mental disorders). Results: Disaster-related PTSD prevalence was 0.0–3.8{%} among adult (ages 18+) WMH respondents and was significantly related to high education, serious injury or death of someone close, forced displacement from home, and pre-existing vulnerabilities (prior childhood family adversities, other traumas, and mental disorders). Of PTSD cases 44.5{%} were among the 5{%} of respondents classified by the model as having highest PTSD risk. Conclusion: Disaster-related PTSD is uncommon in high-income WMH countries. Risk factors are consistent with prior research: severity of exposure, history of prior stress exposure, and pre-existing mental disorders. The high concentration of PTSD among respondents with high predicted risk in our model supports the focus of screening assessments that identify disaster survivors most in need of preventive interventions.
Atwoli L, Stein DJ, King A, Petukhova M, Aguilar-Gaxiola S, Alonso J, Bromet EJ, {De Girolamo} G, Demyttenaere K, Florescu S. {Posttraumatic stress disorder associated with unexpected death of a loved one: Cross-national findings from the world mental health surveys Jose Posada-Villa 24 Margreet ten Have}. Depress Anxiety. 2016;00:1–12.Abstract
Background: Unexpected death of a loved one (UD) is the most commonly reported traumatic experience in cross-national surveys. However, much remains to be learned about posttraumatic stress disorder (PTSD) after this experience. The WHO World Mental Health (WMH) survey ini-tiative provides a unique opportunity to address these issues. Methods: Data from 19 WMH surveys (n = 78,023; 70.1{%} weighted response rate) were collated. Potential predictors of PTSD (respondent sociodemographics, characteristics of the death, history of prior trauma exposure, history of prior mental disorders) after a representative sample of UDs were examined using logistic regression. Simulation was used to estimate overall model strength in targeting individuals at highest PTSD risk. Results: PTSD prevalence after UD averaged 5.2{%} across surveys and did not differ signifi-cantly between high-income and low-middle income countries. Significant multivariate predictors included the deceased being a spouse or child, the respondent being female and believing they could have done something to prevent the death, prior trauma exposure, and history of prior men-tal disorders. The final model was strongly predictive of PTSD, with the 5{%} of respondents having highest estimated risk including 30.6{%} of all cases of PTSD. Positive predictive value (i.e., the pro-portion of high-risk individuals who actually developed PTSD) among the 5{%} of respondents with highest predicted risk was 25.3{%}. Conclusions: The high prevalence and meaningful risk of PTSD make UD a major public health issue. This study provides novel insights into predictors of PTSD after this experience and sug-gests that screening assessments might be useful in identifying high-risk individuals for preventive interventions.
Wachira J, Kamanda A, Embleton L, Naanyu V, Ayuku D, Braitstein P. ‘Pregnancy Has Its Advantages’: The Voices of Street Connected Children and Youth in Eldoret, Kenya. PLOS ONE [Internet]. 2016;11:1-17. WebsiteAbstract
Objective Little is known about the reproductive health or family planning needs of street-connected children and youth in resource-constrained countries. The study objective was to describe how street-connected children and youth (SCCY) in Eldoret, Kenya, perceive pregnancy. Methods This qualitative study was conducted between August 2013 and February 2014. A total of 65 SCCY aged 11–24 years were purposively sampled from the three referral points: 1) A dedicated study clinic for vulnerable children and youth at Moi Teaching and Referral Hospital (MTRH); 2) Primary locations in which street children reside known as “bases/barracks”; and 3) Street youth community-based organizations. In-depth interviews and focus group discussions were audio recorded, transcribed, and translated into English. Content analysis was performed after thematic coding by 4 independent coders. Results The majority of SCCY interviewed were male (69%) and sexually active (81.5%). None had gone beyond primary level of education. The strong desire for SCCY to go through conventional life experiences including marriage and child bearing was evident. Sub-themes around desired pregnancies included: sense of identity with other SCCY, sense of hope, male ego, lineage, source of income, and avoiding stigmatization. The desire for children was highly gendered with male SCCY more focused on their social status in the street community, while for females it was primarily for survival on the street. Female SCCY generally lacked agency around reproductive health issues and faced gender-based violence. Abortions (either assisted or self-induced), infanticide, and child abandonment were reported. Respondents described a lucrative market for babies born to SCCY and alleged that healthcare workers were known to abduct these babies following hospital deliveries. Conclusion Our findings indicate gender differences in the reasons why SCCY become pregnant and have children. We also noted gender inequalities in reproductive health decisions. SCCY friendly interventions that provide tailored reproductive health services are needed.
Mamboleo DM, Njoroge SM, Okaru FN, Ayuku D. The Prevalence of Diarrheal Diseases in Childcare Institutions, Uasin Gishu County, Kenya. International Journal of Research in Environmental Science (IJRES) [Internet]. 2016;2(6):5-11. WebsiteAbstract

Diarrheal disease is one of the leading middle income countries. This study examined diarrheal
diseases among children in Uasin Gishu County’s childcare institutions per age, sex, duration of a child in a
childcare institution, and use of soap in hand washing after visiting the toilet. The study involved 202 children
between ages 6 to 20 years old. There were65.8% boy child and 34.2 girls, 71.3% of these children were
between 6-15 years old. The study found 64.4% children used soap to wash hands after toilet. Use of soap in
hand washing increased with increase in children’s age, with a girl using soap more in hand washing at the rate
of84.1% compared to a boy child. The study learned that 90.1% children had suffered from diarrheal diseases
within 28 days where61.4% boys had suffered from diarrhea. Chi-square analysis showed a significant
relationship between diarrheal diseases and children’s age (P<0.001) while there was a significant relationship
between diarrhea andgender (P<0.001). It was concluded that the prevalence of diarrheal diseases in Uasin
Gishu County child care institutions was 90.1% and that boys were affected more than the girls. Health
education on use of soap in hand-washing after toilet should be intensified as a means of decreasing diarrheal
diseases.


Case JM, Fraser DM, Kumar A, Itika A. The significance of context for curriculum development in engineering education: a case study across three African countries. European Journal of Engineering Education [Internet]. 2016;41:279-292. WebsiteAbstract
Curriculum reform is a key topic in the engineering education literature, but much of this discussion proceeds with little engagement with the impact of the local context in which the programme resides. This article thus seeks to understand the influence of local contextual dynamics on curriculum reform in engineering education. The empirical study is a comparative analysis of the context for curriculum reform in three different chemical engineering departments on the African continent, located in Kenya, Tanzania and South Africa. All three departments are currently engaged in processes of curriculum reform, but the analysis shows how the different contexts in which these efforts are taking place exert strong shaping effects on the processes and outcomes for that reform.

Pages